Recombinant Human Transforming Growth Factor beta-1/TGFB1

Artikelnummer: ABI-32-7784
Artikelname: Recombinant Human Transforming Growth Factor beta-1/TGFB1
Artikelnummer: ABI-32-7784
Hersteller Artikelnummer: 32-7784
Alternativnummer: ABI-32-7784-50UG
Hersteller: Abeomics
Kategorie: Proteine/Peptide
Source: Human Cells. MW :12.8kD. Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. Transforming Growth Factor beta-1 (TGF beta-1) is a secreted protein which belongs to the TGF- beta family. TGF beta-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGF beta-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGF beta-1 peptide. TGF beta-1 may also form heterodimers with other TGF beta family members. It has been found that TGF beta-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
NCBI: 7040
UniProt: P01137
Antibody Type: Recombinant Antibody
Application Verdünnung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez