Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein(N-8His)

Produktübersicht

• Artikelname: Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein(N-8His)
• Artikelnummer: ABI-32-7815
• Hersteller Artikelnummer: 32-7815
• Alternativnummer: ABI-32-7815-50UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide

Produktbeschreibung

Source: Human cells. MW :16.5kD. Recombinant Human NKG2-A/NKG2-B Type II Integral Membrane Protein is produced by our Mammalian expression system and the target gene encoding Arg100-Leu233 is expressed with a 8His tag at the N-terminus. NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. NKG2 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. NKG2A and NKG2B have been given the designation CD159a in the nomenclature of CD antigens.

Produkteigenschaften

• NCBI: 3821
• UniProt: P26715
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez