Recombinant Human SLAM Family Member 2/CD48 (C-Fc-6His)

Produktübersicht

• Artikelname: Recombinant Human SLAM Family Member 2/CD48 (C-Fc-6His)
• Artikelnummer: ABI-32-7851
• Hersteller Artikelnummer: 32-7851
• Alternativnummer: ABI-32-7851-50UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide

Produktbeschreibung

Source: Human Cells. MW :53.1kD. Recombinant Human SLAMF2 is produced by our Mammalian expression system and the target gene encoding Gln27-Ser220 is expressed with a Fc, 6His tag at the C-terminus. CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.

Produkteigenschaften

• NCBI: 962
• UniProt: P09326
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez