Recombinant Human Amyloid beta A4 Precursor Protein-Binding A3/APBA3/X11-gamma (C-6His)

Produktübersicht

• Artikelname: Recombinant Human Amyloid beta A4 Precursor Protein-Binding A3/APBA3/X11-gamma (C-6His)
• Artikelnummer: ABI-32-8042-10
• Hersteller Artikelnummer: 32-8042-10
• Alternativnummer: ABI-32-8042-10-10UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide

Produktbeschreibung

Source: E.coli. MW :15.48kD. Recombinant Human APBA3 is produced by our E.coli expression system and the target gene encoding Met1-Leu138 is expressed with a 6His tag at the C-terminus. Amyloid beta A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimers disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-a and - beta which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.

Produkteigenschaften

• NCBI: 9546
• UniProt: O96018
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez