Recombinant Human Semaphorin-4D/SEMA4D/CD100 (C-Fc)

Produktübersicht

• Artikelname: Recombinant Human Semaphorin-4D/SEMA4D/CD100 (C-Fc)
• Artikelnummer: ABI-32-8456
• Hersteller Artikelnummer: 32-8456
• Alternativnummer: ABI-32-8456-50UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide

Produktbeschreibung

Source: Human Cells. MW :106.4kD. Recombinant Human Semaphorin 4D is produced by our Mammalian expression system and the target gene encoding Met22-Arg734 is expressed with a Fc tag at the C-terminus. Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system, Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.

Produkteigenschaften

• NCBI: 10507
• UniProt: Q92854
• Antibody Type: Recombinant Antibody

Anwendungsbeschreibung

• Application Verdünnung: Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test. Biological Activity : Measured by its ability to binding Activin IIB used funtional ELISA.