Recombinant Human Follicle-Stimulating Hormone a/ beta Dimer
Artikelnummer:
ABI-32-8695
Hersteller Artikelnummer:
32-8695
Alternativnummer:
ABI-32-8695-50UG
Hersteller:
Abeomics
Kategorie:
Proteine/Peptide
Source: Human Cells. MW :10.2&12.5kD. Recombinant Human Follicle-Stimulating Hormone is produced by our Mammalian expression system and the target gene encoding Ala25-Ser116&Asn19-Glu129 is expressed. Human Follicle-stimulating hormone (FSH) is a member of glycoprotein hormones subunit beta family, whichalso includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH). FSH and its familymembers are heterodimers consisting of non-covalently linked a- and beta-subunits. They share an identical asubunit, and beta-subunits vary. FSH has a unique beta-subunit (FSH beta), which confers its specific biologic activityand is responsible for interaction with the FSH-receptor which belongs to a subfamily of GPCRs calledleucine-rich-repeat-containing GPCRs (LGRs). FSH is secreted from the pituitary gland and regulatesreproduction in mammals. FSH stimulates sertoli cell proliferation in testes and supports spermatogenesis inmales, and induces the maturation of ovarian follicles in females.
