Recombinant Human Complement Factor D/Adipsin (C-10His)

Artikelnummer: ABI-32-8791-10
Artikelname: Recombinant Human Complement Factor D/Adipsin (C-10His)
Artikelnummer: ABI-32-8791-10
Hersteller Artikelnummer: 32-8791-10
Alternativnummer: ABI-32-8791-10-10UG
Hersteller: Abeomics
Kategorie: Proteine/Peptide
Source: Human Cells. MW :25.8kD. Recombinant Human Complement factor D is produced by our Mammalian expression system and the target gene encoding Ile26-Ala253 is expressed with a 10His tag at the N-terminus. Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.
NCBI: 1675
UniProt: P00746
Antibody Type: Recombinant Antibody
Application Verdünnung: Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.