Recombinant Human Interleukin-37/IL-37 (C-His)

Artikelnummer: ABI-32-9080-500
Artikelname: Recombinant Human Interleukin-37/IL-37 (C-His)
Artikelnummer: ABI-32-9080-500
Hersteller Artikelnummer: 32-9080-500
Alternativnummer: ABI-32-9080-500-500UG
Hersteller: Abeomics
Kategorie: Proteine/Peptide
Alternative Synonym: Interleukin-37, FIL1 Zeta, IL-1X, Interleukin-1 Family Member 7, IL-1F7, Interleukin-1Homolog 4, IL-1H, IL-1H4, Interleukin-1 Zeta, IL-1 Zeta, Interleukin-1-Related Protein, IL-1RP1, Interleukin-23, IL-37, IL37, FIL1Z, IL1F7, IL1H4, IL1RP1
Source : E. coli,Interleukin-1 family 1 member 7 (IL1F7) is a secretory protein that belongs to the Interleukin 1 cytokine family. Several alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, is a suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. IL1F7b binds to IL18 R with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds interleukin 18 binding protein (IL-18BP), an inhibitory binding protein of interleukin 18 (IL-18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL-18.
Antibody Type: Recombinant Antibody