Recombinant Human Siglec-2/CD22 (C-His)

Produktübersicht

• Artikelname: Recombinant Human Siglec-2/CD22 (C-His)
• Artikelnummer: ABI-32-9083-500
• Hersteller Artikelnummer: 32-9083-500
• Alternativnummer: ABI-32-9083-500-500UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: CD22, SIGLEC2, BL-CAM, SIGLEC-2, Siglec2, SIGLEC2FLJ22814

Produktbeschreibung

Source : Human 293 Cells,B-cell receptor CD22, also known as Siglec-2, is a member of the immunoglobulin superfamily, SIGLEC family of lectins. CD22 is expressed by B-lymphocytes and can mediate B-cell B-cell interactions, as well as the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins, one of which is CD45. As an inhibitory coreceptor of the B-cell receptor (BCR), CD22 plays a central role in establishing signaling thresholds for B-cell activation. CD19 regulates CD22 phosphorylation by augmenting Lyn kinase activity, while CD22 inhibits CD19 phosphorylation via SHP-1.

Produkteigenschaften

• Antibody Type: Recombinant Antibody