Biotinylated Recombinant Human Polymeric Immunoglobulin Receptor/PIgR (C-His)

Produktübersicht

• Artikelname: Biotinylated Recombinant Human Polymeric Immunoglobulin Receptor/PIgR (C-His)
• Artikelnummer: ABI-32-9096-250
• Hersteller Artikelnummer: 32-9096-250
• Alternativnummer: ABI-32-9096-250-250UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: Polymeric Immunoglobulin Receptor, PIgR, Poly-Ig Receptor, Hepatocellular Carcinoma- Associated Protein TB6, PIGR

Produktbeschreibung

Source : Human 293 Cells, Polymeric Immunoglobulin Receptor (pIgR) is a type I transmembrane glycoprotein. pIgR is expressed by secretory epithelial cells with five Ig-like domains in the extracellular region, and transfer to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs and separates the extracellular (known as the secretory component) from the transmembrane segment.