Recombinant Cynomolgus CD163 (C-His)

Produktübersicht

• Artikelname: Recombinant Cynomolgus CD163 (C-His)
• Artikelnummer: ABI-32-9126-500
• Hersteller Artikelnummer: 32-9126-500
• Alternativnummer: ABI-32-9126-500-500UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: CD163 antigenscavenger receptor cysteine-rich type 1 protein M130, CD163 molecule, CD163, GHI/61, HbSR, Hemoglobin scavenger receptor, M130, M130macrophage-associated antigen, MM130, RM3/1

Produktbeschreibung

Source : Human 293 Cells,CD163 is a type I transmembrane glycoprotein that belongs to group B of the cysteine-rich scavenger receptor family. The expression of CD163 is essential and is induced by glucocorticoids, IL-10, IL-6, or endotoxin on circulating monocytes, tissue macrophages. CD163 plays an important role in the clearance of hemoglobin-haptoglobin (Hb-Hp) complexes in the liver, spleen and circulation. A soluble form of CD163 exists in plasma, commonly known as sCD163. sCD163 is generated by ectodomain shedding of the membrane-bound receptor. sCD163 is upregulated in a wide range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gauchers disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.

Produkteigenschaften

• Antibody Type: Recombinant Antibody