Biotinylated Recombinant Human IL-2RA/CD25 (C-Avi&His)

Produktübersicht

• Artikelname: Biotinylated Recombinant Human IL-2RA/CD25 (C-Avi&His)
• Artikelnummer: ABI-32-9153
• Hersteller Artikelnummer: 32-9153
• Alternativnummer: ABI-32-9153-25UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: Interleukin-2 receptor subunit alpha,CD25,p55,TAC antigen,IL2-RA,IL-2R subunit alpha,IL-2-RA,IL2RA,IL-2 receptor subunit alpha

Produktbeschreibung

Source : Human 293 Cells,Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane glycoprotein, contains 2 Sushi (CCP/SCR) domains. IL2RA is expressed on activated T cells and regulatory T cells, and can bind IL2 with low affinity by itself. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. While homodimeric alpha chains (IL2RA) result in low-affinity receptor, homodimeric beta (IL2RB) chains produce a medium-affinity receptor. CD25 has been previously regarded as an activation marker on dendritic cells. Although both murine and human dendritic cells can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.

Produkteigenschaften

• Antibody Type: Recombinant Antibody