PDGFA, PDGF subunit A, PDGF-1, Platelet-Derived Growth Factor Subunit B, Platelet-derived growth factor A chain, Platelet-derived growth factor alpha polypeptide
Source : E. coli,Platelet-derived growth factor alpha (PDGFA) is a member of PDGF family. PDGFA can form disulfide-linked homodimer or heterodimer with PDGFB. PDGF proteins mediate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of two receptors (PDGF R alpha and R beta). PDGFA is expressed in multiple cell types, tissues and is upregulated in various cancers. It is proposed that PDGFA can play a key role in the development and progression of tumor growth by regulating cell proliferation, angiogenesis and metastasis.
Antibody Type:
Recombinant Antibody
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