Recombinant Human Siglec-3/CD33 (C-hFc&His)

Produktübersicht

• Artikelname: Recombinant Human Siglec-3/CD33 (C-hFc&His)
• Artikelnummer: ABI-32-9185-500
• Hersteller Artikelnummer: 32-9185-500
• Alternativnummer: ABI-32-9185-500-500UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: Myeloid Cell Surface Antigen CD33, Sialic Acid-Binding Ig-Like Lectin 3, Siglec-3, gp67, CD33, SIGLEC3

Produktbeschreibung

Source : Human 293 Cells,Myeloid cell surface antigen CD33 is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD33 is a putative adhesion molecule of myelomonocytic-derived cells that regulates sialic-acid dependent binding to cells. In the immune response, may act as an inhibitory receptor upon ligand-induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia.

Produkteigenschaften

• Antibody Type: Recombinant Antibody