Recombinant Cynomolgus Interferon alpha/beta receptor 1/IFNAR1(C-6His)

Produktübersicht

• Artikelname: Recombinant Cynomolgus Interferon alpha/beta receptor 1/IFNAR1(C-6His)
• Artikelnummer: ABI-32-9372
• Hersteller Artikelnummer: 32-9372
• Alternativnummer: ABI-32-9372-50UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta R1, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFNAR1, IFN-aR1, IFNBR, IFNbR

Produktbeschreibung

Source : Human Cells,Interferon alpha/beta receptor 1 (IFN alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

Produkteigenschaften

• Antibody Type: Recombinant Antibody