Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)

Produktübersicht

• Artikelname: Recombinant Cynomolgus CD47 molecule/CD47(C-Fc)
• Artikelnummer: ABI-32-9383-500
• Hersteller Artikelnummer: 32-9383-500
• Alternativnummer: ABI-32-9383-500-500UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: Leukocyte Surface Antigen CD47, Antigenic Surface Determinant Protein OA3, Integrin-Associated Protein, IAP, Protein MER6, CD47, MER6

Produktbeschreibung

Source : Human Cells,CD47(Integrin-Associated Protein,IAP) is a 40-60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

Produkteigenschaften

• Antibody Type: Recombinant Antibody