Recombinant Human Sialic acid-binding lectin/CD33 antigen-like 3/CD33L3

Produktübersicht

• Artikelname: Recombinant Human Sialic acid-binding lectin/CD33 antigen-like 3/CD33L3
• Artikelnummer: ABI-32-9649
• Hersteller Artikelnummer: 32-9649
• Alternativnummer: ABI-32-9649-50UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: Sialic acid-binding Ig-like lectin 15, Siglec-15, CD33 antigen-like 3, CD33L3

Produktbeschreibung

Source : Human Cells,Human Siglec-15 is a transmembrane glycoprotein in the Siglec family. Siglecs are type I transmembrane proteins where the NH3+-terminus is in the extracellular space and the COO-terminus is cytosolic. Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid. These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold. All Siglecs are extended from the cell surface by C2-type Ig domains which have no binding activity. Siglecs differ in the number of these C2-type domains. Human Siglec-15 consists of a 244 amino acid (aa) extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 function is important for osteoclast formation and TRANCE/RANK Ligand signaling in osteoclasts

Produkteigenschaften

• Antibody Type: Recombinant Antibody