Recombinant Human TRAIL R3/TNFRSF10C/CD263 (C-Fc-6His)
Artikelnummer:
ABI-32-9667-500
Hersteller Artikelnummer:
32-9667-500
Alternativnummer:
ABI-32-9667-500-500UG
Hersteller:
Abeomics
Kategorie:
Proteine/Peptide
Alternative Synonym:
Tumor Necrosis Factor Receptor Superfamily Member 10C, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL-R3, TRAIL Receptor Without an
Source : Human Cells,Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesna€(TM)t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.
Antibody Type:
Recombinant Antibody
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