Recombinant Human Activin Receptor 2B/Activin RIIB/ACVR2B (C-Fc-6His)

Produktübersicht

• Artikelname: Recombinant Human Activin Receptor 2B/Activin RIIB/ACVR2B (C-Fc-6His)
• Artikelnummer: ABI-32-9704
• Hersteller Artikelnummer: 32-9704
• Alternativnummer: ABI-32-9704-50UG
• Hersteller: Abeomics
• Kategorie: Proteine/Peptide
• Alternative Synonym: Activin Receptor Type-2B, Activin Receptor Type IIB, ACTR-IIB, ACVR2B

Produktbeschreibung

Source : Human Cells,Activin proteins that belong to the transforming growth factor-beta (TGF-Beta) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities.

Produkteigenschaften

• Antibody Type: Recombinant Antibody