Polyclonal Antibody to NF-KB-p105/p50(Phospho-Ser893), Rabbit
Artikelnummer:
ABI-35-1017
Hersteller Artikelnummer:
35-1017
Alternativnummer:
ABI-35-1017-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Peptide sequence around aa.891~895 (A-S-S-P-V) derived from Human NF-KB-p105.
Alternative Synonym:
KBF1|| NF-kB1|| NFkappaB
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NF-KB1/p105, NF-KB1/p50, REL and NF-KB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
