Polyclonal Antibody to ATF2 (Phospho-Thr73 or 55), Rabbit
Artikelnummer:
ABI-35-1031-50
Hersteller Artikelnummer:
35-1031-50
Alternativnummer:
ABI-35-1031-50-50UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Spezies Reaktivität:
Human, Mouse, Primate, Rat
Immunogen:
Peptide sequence around phosphorylation site of threonine 73 or 55 (T-P-T(p)-R-F) derived from Human ATF2.
Alternative Synonym:
CREB2|| CREBP1
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex. Beausoleil S A, et al. (2004) Proc Natl Acad Sci U S A. 101(33): 12130-12135. Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089. Gupta S, et al. (1995) Science. 267: 389-393. Van Dam H, et al. (1995) EMBO J. 14(8): 1798-1811. Livingstone C, et al. (1995) EMBO J. 14: 1785-1797.
