Polyclonal Antibody to FAK (Phospho-Tyr861), Rabbit
Artikelnummer:
ABI-35-1058
Hersteller Artikelnummer:
35-1058
Alternativnummer:
ABI-35-1058-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 861 (H-I-Y(p)-Q-P) derived from Human FAK.
Alternative Synonym:
FADK 1|| FAK1|| PTK2
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
