Polyclonal Antibody to BCL-2(Phospho-Thr56), Rabbit
Artikelnummer:
ABI-35-1062
Hersteller Artikelnummer:
35-1062
Alternativnummer:
ABI-35-1062-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Peptide sequence around phosphorylation site of threonine 56(G-H-T(p)-P-H) derived from Human BCL-2.
Alternative Synonym:
Bcl-2||PPP1R50
Suppresses apoptosis in a variety of cell systems includingfactor-dependent lymphohematopoietic and neural cells. Regulates cell death bycontrolling the mitochondrial membrane permeability. Appears to function in a feedbackloop system with caspases. Inhibits caspase activity either by preventing the release ofcytochrome c from the mitochondria and/or by binding to the apoptosis-activatingfactor (APAF-1).