Polyclonal Antibody to HDAC8 (Phospho-Ser39), Rabbit
Artikelnummer:
ABI-35-1124
Hersteller Artikelnummer:
35-1124
Alternativnummer:
ABI-35-1124-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC
Spezies Reaktivität:
Human
Immunogen:
Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.
Alternative Synonym:
HD8|| HDA8|| HDACL1
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
