Polyclonal Antibody to PAK1 (Phospho-Thr212), Rabbit

Produktübersicht

• Artikelname: Polyclonal Antibody to PAK1 (Phospho-Thr212), Rabbit
• Artikelnummer: ABI-35-1148-50
• Hersteller Artikelnummer: 35-1148-50
• Alternativnummer: ABI-35-1148-50-50UL
• Hersteller: Abeomics
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Peptide sequence around phosphorylation site of threonine 212 (P-V-T(p)-P-T) derived from Human PAK1.
• Alternative Synonym: p21-activated kinase 1|| PAK-1|| p65-PAK|| Alpha-PAK

Produktbeschreibung

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 5058
• UniProt: Q13153
• Formulierung: Purified
• Target-Kategorie: PAK1 (Phospho-Thr212)

Anwendungsbeschreibung

• Application Verdünnung: Predicted MW: 68kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200