Polyclonal Antibody to Zap-70 (Phospho-Tyr319), Rabbit

Produktübersicht

• Artikelname: Polyclonal Antibody to Zap-70 (Phospho-Tyr319), Rabbit
• Artikelnummer: ABI-35-1152
• Hersteller Artikelnummer: 35-1152
• Alternativnummer: ABI-35-1152-100UL
• Hersteller: Abeomics
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Peptide sequence around phosphorylation site of tyrosine 319 (S-P-Y(p)-S-D) derived from Human Zap-70.
• Alternative Synonym: SRK||STD||TZK||STCD||ZAP-70

Produktbeschreibung

Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not. Salomon AR, et al. (2003) Proc Natl Acad Sci U S A, 100(2): 443-448 Ku GM, et al. (2001) EMBO J, 20(3): 457-465 Tang J, et al. (1999) Proc Natl Acad Sci U S A, 96(17): 9775-9780 Zhao Q, et al. (1996) Mol Cell Biol, 16(12): 6765-6774 Williams BL, et al. (1999) EMBO J, 18(7): 1832-1844 Adjali O, et al. (2005) J Clin Invest, 115(8): 2287-2295.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 7535
• UniProt: P43403
• Formulierung: Purified
• Target-Kategorie: Zap-70 (Phospho-Tyr319)

Anwendungsbeschreibung

• Application Verdünnung: Predicted MW: 70kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200