Polyclonal Antibody to ASK1 (Phospho-Ser966), Rabbit

Produktübersicht

• Artikelname: Polyclonal Antibody to ASK1 (Phospho-Ser966), Rabbit
• Artikelnummer: ABI-35-1170-50
• Hersteller Artikelnummer: 35-1170-50
• Alternativnummer: ABI-35-1170-50-50UL
• Hersteller: Abeomics
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Primate
• Immunogen: Peptide sequence around phosphorylation site of serine 966 (S-I-S(p)-L-P) derived from Human ASK1.
• Alternative Synonym: ASK-1|| M3K5|| MAP3K5|| MAPK/ERK kinase kinase 5|| MAPKKK5

Produktbeschreibung

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death. Zhang W, et al. (2005) J Biol Chem. 280(19): 19036-19044. Fujii K, et al. (2004) Oncogene. 23(29):5099-5104. Goldman EH, et al. (2004) J Biol Chem 2004 Mar 12, 279(11): 10442-10449. Zhang L, et al. (1999) Proc Natl Acad Sci U S A. 96(15): 8511-8515.

Produkteigenschaften

• Klonalität: Polyclonal
• NCBI: 4217
• UniProt: Q99683
• Formulierung: Purified
• Target-Kategorie: ASK1 (Phospho-Ser966)

Anwendungsbeschreibung

• Application Verdünnung: Predicted MW: 155kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100