Polyclonal Antibody to Histone H3.1 (Phospho-Ser10), Rabbit

Artikelnummer: ABI-35-1174-50
Artikelname: Polyclonal Antibody to Histone H3.1 (Phospho-Ser10), Rabbit
Artikelnummer: ABI-35-1174-50
Hersteller Artikelnummer: 35-1174-50
Alternativnummer: ABI-35-1174-50-50UL
Hersteller: Abeomics
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IF, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Immunogen: Peptide sequence around phosphorylation site of serine 10 (R-K-S(p)-T-G) derived from Human Histone H3.1.
Alternative Synonym: H3/b||H3FB
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Dai J, et al. (2005) Genes Dev 19(4): 472-488. Yih LH, et al. (2005) Carcinogenesis 26(1): 53-63.
Klonalität: Polyclonal
NCBI: 8350
UniProt: P68431
Formulierung: Purified
Target-Kategorie: Histone H3.1 (Phospho-Ser10)
Application Verdünnung: Predicted MW: 17kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200