Polyclonal Antibody to p21Cip1 (Phospho-Thr145), Rabbit
Artikelnummer:
ABI-35-1193-50
Hersteller Artikelnummer:
35-1193-50
Alternativnummer:
ABI-35-1193-50-50UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Peptide sequence around phosphorylation site of threonine 145 (R-Q-T(p)-S-M) derived from Human p21Cip1.
Alternative Synonym:
CAP20|| CDK-interacting protein 1|| CDKN1|| CDKN1A|| CDN1A
May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.
