Polyclonal Antibody to p56Dok-2 (Phospho-Tyr299), Rabbit
Artikelnummer:
ABI-35-1254
Hersteller Artikelnummer:
35-1254
Alternativnummer:
ABI-35-1254-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.
Alternative Synonym:
DOK2
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation Feng Cong, et,al. (1999) Mol. Cell. Biol , 19: 8314 - 8325. Serge Lemay, et,al. (2000) Mol. Cell. Biol , 20: 2743 - 2754. Ute Schaeper, et,al.(2000) J. Cell Biol , 149: 1419. Miyuki Honma, et,al. (2006) Genes Cells, 11: 143 - 151.
