Polyclonal Antibody to PI3 Kinase p85/p55(phospho-Tyr467/199)Antibody, Rabbit
Artikelnummer:
ABI-35-1306-50
Hersteller Artikelnummer:
35-1306-50
Alternativnummer:
ABI-35-1306-50-50UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3 Kinase p85/p55.
Alternative Synonym:
p85||AGM7||p85-ALPHA||p55||p55-GAMMA
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
