Polyclonal Antibody to Paxillin (phospho-Tyr88), Rabbit
Artikelnummer:
ABI-35-1321
Hersteller Artikelnummer:
35-1321
Alternativnummer:
ABI-35-1321-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, WB
Spezies Reaktivität:
Human
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 88 (P-V-Y(p)-G-S) derived from Human Paxillin.
Alternative Synonym:
Paxillin, Pxn
An antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells (Ref.1). This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) (paxillus means small stake or peg in Latin) as a protein tethered to the membrane at focal adhesions
