Polyclonal Antibody to syk (phospho-Tyr323), Rabbit
Artikelnummer:
ABI-35-1328
Hersteller Artikelnummer:
35-1328
Alternativnummer:
ABI-35-1328-100UL
Hersteller:
Abeomics
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y(p)-E- P) derived from Human syk.
Alternative Synonym:
Spleen tyrosine kinase
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion
