Anti-CD14 (Monocyte / Macrophage Marker) Monoclonal Antibody(Clone: LPSR/2397), Clone: [LPSR/2397], Mouse

Produktübersicht

• Artikelname: Anti-CD14 (Monocyte / Macrophage Marker) Monoclonal Antibody(Clone: LPSR/2397), Clone: [LPSR/2397], Mouse
• Artikelnummer: ABI-36-3532
• Hersteller Artikelnummer: 36-3532
• Alternativnummer: ABI-36-3532-100UG
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment of human CD14 protein (around aa 25-148) (exact sequence is proprietary)
• Alternative Synonym: Lipopolysaccharide receptor, LPS-R, LPSR, Mo2, Monocyte Differentiation Antigen 14, Myeloid cell-specific leucine-rich glycoprotein

Produktbeschreibung

Recognizes a protein of 55kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [LPSR/2397]
• NCBI: 929
• UniProt: P08571

Anwendungsbeschreibung

• Application Verdünnung: Western Blot (1-2ug/ml),Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95&degC followed by cooling at RT