Anti-Lewis A (Blood Group Antigen) Monoclonal Antibody(Clone: 7LE), Clone: [7LE], Mouse

Produktübersicht

• Artikelname: Anti-Lewis A (Blood Group Antigen) Monoclonal Antibody(Clone: 7LE), Clone: [7LE], Mouse
• Artikelnummer: ABI-36-3719-20
• Hersteller Artikelnummer: 36-3719-20
• Alternativnummer: ABI-36-3719-20-20UG
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FACS, IF, IHC
• Spezies Reaktivität: Human, Mouse
• Immunogen: Mucins isolated from ovarian cyst fluid
• Alternative Synonym: Lewis A antigen

Produktbeschreibung

Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [7LE]

Anwendungsbeschreibung

• Application Verdünnung: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min a