Anti-Cytokeratin, Multi (Epithelial Marker) Monoclonal Antibody(Clone: rKRT/457), Clone: [rKRT/457], Mouse
Artikelnummer:
ABI-36-3772
Hersteller Artikelnummer:
36-3772
Alternativnummer:
ABI-36-3772-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
Keratin-enriched preparation from cultured human epithelial cells
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8), 56.5kDa (CK10), 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),
Fig. 1: Formalin-fixed, paraffin-embedded human Skin stained with Multi-Cytokeratin Mouse Recombinant Monoclonal Antibody (rKRT/457).