Anti-Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Monoclonal Antibody(Clone: AE-1), Clone: [AE-1], Mouse

Produktübersicht

• Artikelname: Anti-Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Monoclonal Antibody(Clone: AE-1), Clone: [AE-1], Mouse
• Artikelnummer: ABI-36-3782
• Hersteller Artikelnummer: 36-3782
• Alternativnummer: ABI-36-3782-100UG
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FACS, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Human epidermal keratin
• Alternative Synonym: K1B, KRT1B, Keratin, type II cytoskeletal 1b, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B, Type-II Keratin Kb39

Produktbeschreibung

This MAb recognizes the 56.5kDa (CK10), 50kDa (CK14), 50kDa (CK15), 48kDa (CK16), 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI , 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [AE-1]
• NCBI: 374454
• UniProt: Q7Z794

Anwendungsbeschreibung

• Application Verdünnung: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA,