Anti-Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal Antibody(Clone: DT101+ BC199 + T311 + HMB45), Clone: [DT101+ BC199 + T311 + HMB45], Mouse

Produktübersicht

• Artikelname: Anti-Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal Antibody(Clone: DT101+ BC199 + T311 + HMB45), Clone: [DT101+ BC199 + T311 + HMB45], Mouse
• Artikelnummer: ABI-36-3784-20
• Hersteller Artikelnummer: 36-3784-20
• Alternativnummer: ABI-36-3784-20-20UG
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant hMART-1 protein (DT101 & BC199), Extract of pigmented melanoma metastases from lymph nodes (HMB45), Recombinant tyrosinase protein (T311)
• Alternative Synonym: Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A, PMEL17

Produktbeschreibung

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [DT101+ BC199 + T311 + HMB45]
• NCBI: 2315
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),

Bilder

Fig. 1: Formalin-fixed, paraffin-embedded human Melanoma stained with Melanoma Marker Mouse Monoclonal (DT101+ BC199 + T311 + HMB45).