Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) Monoclonal Antibody (Clone: MAPK-YT), Clone: [MAPK-YT], Mouse

Produktübersicht

• Artikelname: Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&2) Monoclonal Antibody (Clone: MAPK-YT), Clone: [MAPK-YT], Mouse
• Artikelnummer: ABI-39-1046
• Hersteller Artikelnummer: 39-1046
• Alternativnummer: ABI-39-1046-100UG/VIAL
• Hersteller: Abeomics
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ICC, WB
• Spezies Reaktivität: Human
• Immunogen: A synthetic peptide containing 11 amino acids, HTGFLTpEYpVAT, corresponding to the phosphorylated form of ERK-activation loop conjugated to KLH.
• Alternative Synonym: Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3, 2.7.11.24, ERT2, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase isoform p44, p44-MAPK, MNK1, Microtubule-associated protein 2 kinase, p44-ERK1, Mapk3, Erk1, Prkm3

Produktbeschreibung

In mammalian cells, a variety of extracellular stimuli generate intracellular signals that converge on a limited number of so-called mitogen-activated protein(MAP) kinase pathways. The central core of each MAP kinase(MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase(MAPKKK) phosphorylates and activates a specific MAPK kinase(MAPKK), which then activates a specific MAPK. Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MAPK-YT]
• NCBI: 50689
• UniProt: P21708
• Reinheit: Ascites
• Target-Kategorie: Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 3
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Application Verdünnung: Western blot : 0.25-0.5µg/ml, Immunohistochemistry(Paraffin-embedded Section) : 0.4-1µg/ml, Immunocytochemistry : 1µg/ml