E. coli-derived rat IL13 recombinant protein (Position: P22-H131). Rat IL13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL13, respectively.
Alternative Synonym:
Interleukin-13, IL-13, T-cell activation protein P600, Il13, Il-13
IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4R?) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
