Anti-Thymidylate Synthase Monoclonal Antibody (Clone:IHC697)-Ready to Use, Clone: [IHC697], Mouse
Artikelnummer:
ABI-44-1190
Hersteller Artikelnummer:
44-1190
Alternativnummer:
ABI-44-1190-7ML
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Alternative Synonym:
TYMS, TS, OK/SW-cl.29, TSase
Thymidylate Synthase (TS) is a crucial enzyme responsible for the synthesis of 2-deoxythymidine-5-monophosphate (dTMP) a precursor for thymidylate which is necessary for DNA replication and repair from 2-deoxyuridine-5-monophosphate (dUMP). In terms of cancer, TS is an important target for cancer treatment as the inhibition of TS and therefore nucleotide synthesis necessary for cell growth has shown to be a vital part for successful treatment against colorectal, pancreatic and breast cancers.