Human 2B4 / CD244 / SLAMF4 Protein, His Tag, Unconjugated
Artikelnummer:
ABS-2B4-H5224-100UG
Hersteller Artikelnummer:
2B4-H5224-100ug
Alternativnummer:
ABS-2B4-H5224-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Iglike (immunoglobulinlike) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP2 and SH2D1A/SAP. SLAMF4 modulate other receptorligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family. - Proteine/Peptide