Human Latent Activin A / INHBA Protein, His Tag, Unconjugated

Artikelnummer: ABS-ACA-H424X-100UG
Artikelname: Human Latent Activin A / INHBA Protein, His Tag, Unconjugated
Artikelnummer: ABS-ACA-H424X-100UG
Hersteller Artikelnummer: ACA-H424x-100ug
Alternativnummer: ABS-ACA-H424X-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely inhibin down regulates FSH synthesis and inhibits FSH secretion.Activins are nonglycosylated homodimers or heterodimers of various beta subunits (betaA, betaB, betaC, and betaE in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two betaA chains. The betaA subunit can also heterodimerize with a betaB or betaC subunit to form Activin AB and Activin AC, respectively. The 14 kDa mature human betaA chain shares 100% amino acid sequence identity with bovine, feline, mouse, porcine, and rat betaA. - Proteine/Peptide
Molekulargewicht: 45.9 kDa
Tag: N-6*His
NCBI: 08476
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: Activin A
Immobilized Human Latent Activin A, His Tag (Cat. No. ACA-H424x) at 10 µg/mL (100 µL/well) can bind Human ACVR2A, Fc Tag (Cat. No. ACA-H5269) with a linear range of 0.6-20 ng/mL (QC tested).
Immobilized Human Latent Activin A, His Tag (Cat. No. ACA-H424x) at 5 µg/mL (100 µL/well) can bind Biotinylated Human Activin RIIB Protein, His,Avitag (Cat. No. ACB-H82E3) with a linear range of 0.005-0.313 µg/mL (Routinely tested).
Human Latent Activin A, His Tag on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
ACA-H424x-100ug