Biotinylated Human Activin RIIB Protein, His,Avitag(TM)

Produktübersicht

• Artikelname: Biotinylated Human Activin RIIB Protein, His,Avitag(TM)
• Artikelnummer: ABS-ACB-H82E3-200UG
• Hersteller Artikelnummer: ACB-H82E3-200ug
• Alternativnummer: ABS-ACB-H82E3-200UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

Activin receptor type2B (ACVR2B) is also known as ActRIIB and MGC116908, ACVR2B is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factorbeta (TGFbeta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligandbinding extracellular domain with cysteinerich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3 to 4fold higher affinity for the ligand than activin A type II receptor. Defects in ACVR2B are the cause of visceral heterotaxy autosomal type 4 (HTX4). - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 17.2 kDa
• Tag: C-10*His & C-Avi
• NCBI: 13705
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: Activin RIIB

Bilder

Immobilized Human Latent Activin A, His Tag (Cat. No. ACA-H424x) at 5 µg/mL (100 µL/well) can bind Biotinylated Human Activin RIIB Protein, His,Avitag (Cat. No. ACB-H82E3) with a linear range of 0.005-0.313 µg/mL (QC tested).

Immobilized Human Activin A Protein, Tag Free (Cat. No. ACA-H421b) at 5 µg/mL (100 µL/well) can bind Biotinylated Human Activin RIIB Protein, His,Avitag (Cat. No. ACB-H82E3) with a linear range of 0.3-5 ng/mL (Routinely tested).

Biotinylated Human Activin RIIB Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

ACB-H82E3-200ug