Human ADIPOR1 Protein, Flag,His Tag (Detergent), Unconjugated, Insect 100 ug

Produktübersicht

• Artikelname: Human ADIPOR1 Protein, Flag,His Tag (Detergent), Unconjugated, Insect 100 ug
• Artikelnummer: ABS-AD1-H55D3-100UG
• Hersteller Artikelnummer: AD1-H55D3-100ug
• Alternativnummer: ABS-AD1-H55D3-100UG
• Hersteller: AcroBiosystems
• Wirt: Insect
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Adiponectin Receptor 1 (AdipoR1) is a pivotal receptor mediating the metabolic effects of the adipokine adiponectin. AdipoR1 features seven transmembrane domains with an intracellular Nterminus and an extracellular Cterminus responsible for adiponectin binding. AdipoR1 is predominantly expressed in skeletal muscle and can activate adenosine monophosphateactivated protein kinase (AMPK). This activation leads to the phosphorylation of ACC and the subsequent upregulation of CPT1A, which together critically enhance mitochondrial fatty acid betaoxidation. Dysfunction in this AdipoR1driven pathway is closely associated with impaired fatty acid oxidation and dyslipidemia. AdipoR1 represents a significant therapeutic target for metabolic disorders involving lipid dysregulation. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 36.8 kDa
• Tag: N-Flag & C-10*His
• NCBI: 96
• Puffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Reinheit: 90%
• Formulierung: Liquid
• Target-Kategorie: ADIPOR1

Bilder

Immobilized Human ADIPOR1 Protein, Flag,His Tag (Cat. No. AD1-H55D3) at 1 µg/mL (100 µL/well) can bind Anti-ADIPOR1 Antibody, Rabbit IgG1 with a linear range of 0.2-5 ng/mL (QC tested).

AD1-H55D3-100ug