Cynomolgus ADAM9 Protein, His Tag (active enzyme, MALS verified), Unconjugated, Human 500 ug

Produktübersicht

• Artikelname: Cynomolgus ADAM9 Protein, His Tag (active enzyme, MALS verified), Unconjugated, Human 500 ug
• Artikelnummer: ABS-AD9-C52H7-500UG
• Hersteller Artikelnummer: AD9-C52H7-500ug
• Alternativnummer: ABS-AD9-C52H7-500UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Konjugation: Unconjugated

Produktbeschreibung

ADAM9 (A disintegrin and a metalloprotease 9) is a membraneanchored protein that participates in a variety of physiological functions, primarily through the disintegrin domain for adhesion and the metalloprotease domain for ectodomain shedding of a wide variety of cell surface proteins. ADAM9 influences the developmental process, inflammation, and degenerative diseases.Recently, increasing evidence has shown that ADAM9 plays an important role in tumor biology. Overexpression of ADAM9 has been found in several cancer types and is correlated with tumoraggressiveness and poor prognosis. In addition, through either proteolytic or nonproteolytic pathways, ADAM9 promotes tumor progression, therapeutic resistance, and metastasis of cancers.Therefore, comprehensively understanding the mechanism of ADAM9 is crucial for the development of therapeutic anticancer strategies. In this review, we summarize the current understanding of ADAM9 in biological function, pathophysiological diseases, and various cancers. Recent advances in therapeutic strategies using ADAM9related pathways are presented as well. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 55.3 kDa
• Tag: C-10*His
• NCBI: 0
• Puffer: 20 mM Tris, 500 mM NaCl, pH7.5
• Reinheit: 95%
• Formulierung: Liquid
• Target-Kategorie: ADAM9

Bilder

Immobilized Cynomolgus ADAM9, His Tag (Cat. No. AD9-C52H7) at 1 µg/mL (100 µL/well) can bind Izeltabart with a linear range of 0.03-1 ng/mL (QC tested).

Cynomolgus ADAM9, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

AD9-C52H7-500ug