Human ADORA2A Protein, Flag,His Tag (Detergent), Unconjugated 500 ug

Produktübersicht

• Artikelname: Human ADORA2A Protein, Flag,His Tag (Detergent), Unconjugated 500 ug
• Artikelnummer: ABS-ADA-H52D3-500UG
• Hersteller Artikelnummer: ADA-H52D3-500ug
• Alternativnummer: ABS-ADA-H52D3-500UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

This gene encodes a member of the guanine nucleotidebinding protein (G protein)coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are sevenpass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A readthrough transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiledcoil domains 1like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be noncoding. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 61.1 kDa
• Tag: N-Flag & C-10*His
• NCBI: 29274
• Puffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Reinheit: 90%
• Formulierung: Liquid
• Target-Kategorie: ADORA2A

Bilder

Immobilized Human ADORA2A Protein, Flag,His Tag (Cat. No. ADA-H52D3) at 5 µg/mL (100 µL/well) on a Nickel Coated plate (Cat. No. SP-16) can bind Anti-ADORA2AAntibody,HumanIgG1 with a linear range of 0.05-1 ng/mL (QC tested).

Human ADORA2A Protein, Flag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.