Biotinylated Human Apolipoprotein E / APOE4 Protein, His,Avitag(TM) (MALS verified)
Artikelnummer:
ABS-APE-H52E7-25UG
Hersteller Artikelnummer:
APE-H52E7-25ug
Alternativnummer:
ABS-APE-H52E7-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Biotin
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoproteinmediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to highdensity lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptorrelated proteins LRP1, LRP2 and LRP8 and the very lowdensity lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOEcontaining lipoprotein particles. - Proteine/Peptide
