Biotinylated Human APRIL / TNFSF13 Protein, Fc,Avitag(TM)

Produktübersicht

• Artikelname: Biotinylated Human APRIL / TNFSF13 Protein, Fc,Avitag(TM)
• Artikelnummer: ABS-APL-H82F5-25UG
• Hersteller Artikelnummer: APL-H82F5-25ug
• Alternativnummer: ABS-APL-H82F5-25UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

APRIL(a proliferationinducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL2, TRDL1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferationinducing ligand (APRIL) serve in the generation and maintenance of mature Blymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFFAPRIL heteromers of different stoichiometries have distinct receptorbinding properties and activities. In addition, expression of APRIL was regulated by miR145 in GC cells. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 44.6 kDa
• Tag: N-Fc & N-Avi
• NCBI: 75888
• Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: APRIL

Bilder

Immobilized Human BCMA, His Tag (Cat. No. BCA-H522y) at 2 µg/mL (100 µL/well) can bind Biotinylated Human APRIL, Fc,Avitag (Cat. No. APL-H82F5) with a linear range of 1-20 ng/mL (QC tested).

Immobilized Human BCMA, His Tag (Cat. No. BCA-H522y) at 2 µg/mL (100 µL/well) can bind pre-mixed increasing concentrations of Anti-BCMA MAb (Mouse IgG1, the antibody was co developed by SCT and ACRObiosystems) and 0.05 µg/mL (100 µL/well) Biotinylated Human APRIL, Fc,Avitag (Cat. No. APL-H82F5) with a half maximal inhibitory concentration (IC50) of 4.624 µg/mL (Routinely tested).

APL-H82F5-25ug

Biotinylated Human APRIL, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.