Human APP Protein, His Tag (active enzyme, MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human APP Protein, His Tag (active enzyme, MALS verified), Unconjugated
• Artikelnummer: ABS-APP-H52H3-100UG
• Hersteller Artikelnummer: APP-H52H3-100ug
• Alternativnummer: ABS-APP-H52H3-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. It has three predominant splice variants: APP695, APP751, and APP770. The majority of APP is cleaved at the plasma membrane by the alphasecretase in the nonamyloidogenic pathway. The amyloidogenic pathway starts with betasecretase cleavage by BACE1 on the Nterminal part of the Abeta domain, releasing sAPPbeta from a membraneanchored fragment named betaCTF or C99, which is subsequently cleaved by gammasecretase to release Abeta. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 77.9 kDa
• Tag: C-10*His
• NCBI: 05067
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: APP

Bilder

Human APP Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.